Ultrafine anaphase bridges
Webof ultrafine anaphase bridges (UFBs), atype of chromosome non-disjunction. Topo IIα has been reported to resolve DNA anaphase threads, possibly accounting for the increase in … Web16 May 2011 · Intriguingly replication fork stalling and DNA breakage correlate with the appearance of structures that are analogous to ultrafine anaphase bridges (UFBs), which frequently form at fragile sites during mitosis in human cells, and are thought to occur when replication is incomplete (18,19). We propose that a failure of replication restart at non …
Ultrafine anaphase bridges
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WebNew insights into the formation and resolution of ultrafine anaphase bridges. Semin Cell Dev Biol (2011), 22(8): 906-12. Chan KL, Hickson ID. On the origins of ultra-fine anaphase bridges. Cell Cycle (2009), 8(19): 3065-6. Cheok CF, Bachrati CZ, Chan KL, Ralf C, Wu L, Hickson ID. Roles of the Bloom's syndrome helicase in the maintenance of ... WebNational Center for Biotechnology Information
WebUltrafine anaphase bridges (UFBs) are a potential source of genome instability that is a hallmark of cancer. UFBs can arise from DNA catenanes at centromeres/rDNA loci, late … Web(A) HeLa cells were transfected with siControl or siTDP-43 and ultrafine anaphase bridges (UFBs) were visualized using both anti-PICH and anti-BLM antibodies. Representative …
Web30 Apr 2014 · Abstract and Figures. Ultra-fine DNA bridges (UFBs) are a recently identified class of mitotic DNA structures that cannot be visualized using conventional DNA staining … WebChromatin bridge is a mitotic occurrence that forms when telomeres of sister chromatids fuse together and fail to completely segregate into their respective daughter cells. …
Web12 Mar 2015 · Thus far TOPBP1 localisation to ultra-fine anaphase bridges (UFBs) has been reported only in yeast Saccharomyces cerevisiae and the transformed avian B-lymphoblastoid cell line DT40 16. Therefore, we decided to test if this was also the case in human transformed and importantly, primary cells.
WebT1 - Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier. AU - Sofueva, Sevil. AU - Osman, Fekret. AU - Lorenz, Alexander. AU … cheap bosch fridge freezerWeb12 Mar 2015 · Here, the authors report that topoisomerase IIβ binding protein 1 recruits topoisomerase IIα to centromere-associated ultra-fine anaphase bridges to enable their … cute school bus clipartWeb8 Mar 2024 · TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability. PubMed Central. Germann, Susanne M.; Schramke, Vera; Pedersen, Rune Troelsgaard; … cute school backpacks for teensWebUltrafine anaphase bridges (UFBs) result from a defect in sister chromatid segregation during anaphase. They arise from particular DNA structures, mostly generated at specific … cute school backpacks tumblrWebMost DNA double-strand breaks (DSBs) in S- and G2-phase cells are repaired accurately by Rad51-dependent sister chromatid recombination. However, a minority give rise to gross … cute school bus drawingsWebUltra-fine anaphase DNA bridges (UFBs) were discovered in our group over 10 years ago. They are nucleosome-free DNA threads that connect the separating sister DNA masses … cute school binder decorationsWeb1 Jun 2024 · Although chromatin bridges and lagging chromatin are always pathological (generating aneuploidy or complex genomic rearrangements), the main subject of this article, the ultrafine anaphase bridges, might, in addition to potentially driving genomic instability, play critical roles for the maintenance of chromosome structure in rapidly ... cheap bora bora packages