Web19 nov. 2024 · MEF2C has been shown to be a critical transcription factor for neurodevelopment, whose loss-of-function mutation in humans results in MEF2C haploinsufficiency syndrome (MHS), a severe form of autism spectrum disorder (ASD)/intellectual disability (ID). Here, we use patient hiPSC-derived cerebrocortical … Web22 feb. 2016 · Previous work had shown that myocyte enhancer factor 2C (MEF2C) is indispensable for the lymphoid fate decision, yet the specific mechanism of action …
Gene - MEF2C
WebMEF2C haploinsufficiency syndrome was recently recognized as a neurodevelopmental disorder. Severe intellectual disability with inability to speak and epilepsy are universal … Web14 apr. 2024 · In this study, we identify a source of Mfge8 within human gastric antrum muscles using spatial transcriptomic analysis. We show that Mfge8 is expressed in subpopulations of Mef2c + perivascular cells within the submucosa layer of the gastric antrum. Mef2c is expressed in subpopulations of NG2 + and PDGFRB + pericytes. lapsiystävällinen kysely
MEF2C - an overview ScienceDirect Topics
Web1 apr. 2024 · MEF2C was the preferred candidate to study given its known function as an oncogene in lymphoid malignancies ( 35) and cooperation with MLL -rearranged AML ( 19 ). The observed MEF2C pS222 peptide was distinct from the related MEF2A, MEF2B, and MEF2D peptides (Supplementary Fig. S1C). Web27 aug. 2024 · As changes in neuronal activity may be observed across sleep-wake states, we investigated the possible role of MEF2C as a key regulator of sleep-related control of gene expression, sleep-related modulation of synaptic function and sleep-need correlated SWS-SWA buildup and resolution. Results Figure 1A Figure 1 with 3 supplements see … WebAntibodies that detect MEF2C can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target MEF2C in Human, Mouse, Rat, Zebrafish and Non-human primate samples. Our MEF2C monoclonal and polyclonal antibodies are developed in Mouse … lapsiystävällinen oulu