Nettet1. okt. 2024 · Inspired by the pioneering Hofmann–Löffler–Freytag (HLF) reaction that enables pyrrolidine formation via remote C (sp 3 )–H functionalization of aliphatic amines (Scheme 9 ), 3 recently many research groups, for example, Li, 64,65 Cook, 66 Muñiz, 67 Studer, 68,69 Yu, 70,71 Zhu, 72,73 Nagib, 74 Roizen, 75 Wang, 76 Leonori, 77 Hong, … Nettet12. okt. 2016 · In the latter process—a subset of the classical Hofmann–Löffler–Freytag reaction—amidyl radicals remove hydrogen atoms from unactivated aliphatic C–H bonds17,18,19,20,21.
Hofmann Löffler-Freytag reaction
Nettet5. feb. 2012 · Name Reactions in Organic Synthesis - September 2006. Skip to main content Accessibility help We use cookies to distinguish you from other users and to … Nettet1. jan. 2014 · Reaction Formation These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the … mai kitchen virginia highlands
Hofmann–Löffler–Freytag反应_Rev - 搜狐
Nettet14. mar. 2010 · Request PDF Hofmann–Löffler–Freytag reaction Formation of pyrrolidines or piperidines by thermal or photochemical decomposition of protonated N … NettetHofmann—Löffler—Freytag reaction Formation of pyrrolidines or piperidines by thermal or photochemical decomposi- tion of protonated N-haloamines. 2. -OH Example 12 HO Example 24 RI homolytic cleavage chloroammonium salt 1 ,5-hydrogen atom transfer OH . NH NH 1. NaOCl, 95% 2. TFA, hv, 87% 3. NaOH, MeOH. 76% Nettet15. sep. 2010 · The synthesis of pyrrolidine or piperidine derivatives by thermal or photochemical decomposition of the protonated aliphatic N-haloamines is generally … mai king of fighters cosplay