WebSurprisingly, thalamic axons (which do not express Tbr1) deviated into the external capsule and amygdala regions, without entering the cortex. Conversely, in most Gbx2 mutants, thalamic axons were reduced in number and grew no farther than the subpallium. WebApr 15, 2009 · Relatively little is known about the development of the thalamus,especially its differentiation into distinct nuclei. We demonstrate here that Gbx2-expressing cells in mouse diencephalon contribute to the entire thalamic nuclear complex. However, the neuronal precursors for different thalamic nuclei display temporally distinct Gbx2 …
Gbx2 plays an essential but transient role in the formation of thalamic ...
WebFeb 1, 2002 · The differential expression of Gbx2 within the dorsal thalamus clearly corresponds with the existence of four primary subdivisions identified in a previous study from this laboratory [13]: the anteroventral region and dorsal, intermediate, and ventral tiers. The subhabenular region turned out not to express Gbx2; this possibly implies it needs ... WebApr 15, 2009 · The thalamus relays information to the cortex and consists of dozens of distinct groups of neuronal cell bodies called thalamic nuclei. How do these separate nuclei form during development? On p. 1317, James Li and co-workers use an inducible genetic fate-mapping technique to demonstrate the importance of the homeobox transcription … horsefly hotel
Gbx2 gastrulation brain homeobox 2 [ (house mouse)]
WebWe assigned each lizard neuron type to a thalamic nucleus by analyzing in situ hybridizations for cluster-specific or area-specific genes (e.g., transcription factors tcf7l2, zic1, foxp2, or gbx2; effector genes such as opn4, expressed in dorsomedial thalamic neurons; cbln1 in dorsolateral thalamic neurons; vip in neurons from the nucleus ... WebMar 11, 2024 · Transient expression of Cyp26b1 in the PFC does not occur in the absence of thalamus–cortex interactions in Gbx2 mutant mice. A–F, Thalamus–PFC disconnection in Gbx2 mutant mice. A, B, Immunostaining for NetrinG1 at E16.5. In control mice, NetrinG1-labeled thalamocortical axons are visible in coronal sections of frontal cortex. WebApr 1, 2003 · The thalamus and cortex develop synchronously — virtually all the thalamic neurons in the rat are born between embryonic day (E) 13 and E19, which coincides with … horsefly habitat