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Dual specificity protein phosphatase 1

WebActs as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins (PubMed:9187108, PubMed:9256433). Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, … WebApr 7, 2024 · The primary structure of PPP5C can be mainly divided into three parts, the N-terminal tetrapeptide repeat (TPR) domain (residues 28–129), the middle phosphatase …

Crystal Structure of the Dual Specificity Protein Phosphatase VHR

WebDual specificity phosphatase 15 (Dusp15) represses myelin gene expression. Mag, Mbp, connexin 32 (Cx32), peripheral myelin protein 22 (Pmp22), and Srebp-1c mRNA levels … inc51 https://baileylicensing.com

DUSP4 Gene - GeneCards DUS4 Protein DUS4 Antibody

WebMar 21, 2024 · DUSP1 (Dual Specificity Phosphatase 1) is a Protein Coding gene. Diseases associated with DUSP1 include Intellectual Developmental Disorder, X-Linked 108 and Ovarian Cancer . Among its … WebPTHR45961:SF5 DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 1 hit; PTHR45961 IP21249P 1 hit; PRINTS. PR01908 ADSPHPHTASE; PR01910 ADSPHPHTASEB; PROSITE. View protein in PROSITE; PS00383 TYR_PHOSPHATASE_1 1 hit; PS50056 TYR_PHOSPHATASE_2 1 hit; PS50054 TYR_PHOSPHATASE_DUAL 1 hit; Pfam. … WebDual specificity phosphatase 1 (DUSP1), a negative regulator of the mitogen‑activated protein kinase (MAPK) signaling pathway, has anti‑inflammatory properties. In the present study, the expression of DUSP1 was investigated in human OA fibroblast‑like synoviocytes (FLSs), human normal FLSs and OA FLSs pretreated with dexamethasone at the ... included offence

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Dual specificity protein phosphatase 1

Role of Dual Specificity Phosphatase in Stress and

WebApr 10, 2024 · dual specificity protein phosphatase CDC14A isoform 2 Download Models. Job ID Status Method Username Target Length Date (PST) Expiration Date … WebDec 8, 2024 · Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. …

Dual specificity protein phosphatase 1

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WebOct 21, 2024 · Encodes a protein tyrosine phosphatase Propyzamide-Hypersensitive 1 (PHS1). One of the mutant alleles, phs1-1, is hypersensitive to the microtubule-destabilizing drug propyzamide, suggesting that PHS1 may be involved in phosphorylation cascades that control the dynamics of cortical microtubules in plant cells. A second allele, phs1-3, is … WebJan 1, 2024 · Download Citation On Jan 1, 2024, Ruibing Li and others published Interaction between dual specificity phosphatase-1 and cullin-1 attenuates alcohol-related liver disease by restoring p62 ...

WebApr 7, 2024 · The primary structure of PPP5C can be mainly divided into three parts, the N-terminal tetrapeptide repeat (TPR) domain (residues 28–129), the middle phosphatase domain (residues 175–490), and the C-terminal α-J helix (residues 490–499) [4] (Fig. 1 A).The TPR domain contains 34 amino acids which exert the autoinhibition functions of … WebJan 1, 2015 · Dual-specificity protein phosphatase 1 (DUSP1), known also as MAP kinase phosphatase 1 (MKP1), is implicated in metabolism and energy expenditure. Mice lacking DUSP1 are resistant to high-fat diet-induced obesity. However, the expression of DUSP1 has not been investigated in human obesity. In the current study, we compared …

WebPTPN13 is a soluble and cytosolic non-receptor protein that can be translocated to the sub-membranous and nuclear compartments [ 7] during mitosis [ 8 ]. The PTPN13 gene is located on chromosome 4q21.3 and encodes the non-receptor protein phosphatase with the highest molecular weight (270 kDa; 2466 amino acids) [ 9 ]. WebJul 5, 2004 · PTHR47100:SF5 DUAL SPECIFICITY PROTEIN PHOSPHATASE PHS1 1 hit; PROSITE. View protein in PROSITE; PS00383 TYR_PHOSPHATASE_1 1 hit; PS50056 TYR_PHOSPHATASE_2 1 hit; PS50054 TYR_PHOSPHATASE_DUAL 1 hit; Pfam. View protein in Pfam; PF09192 Act-Frag_cataly 1 hit; PF00782 DSPc 1 hit; SMART.

WebMar 29, 2024 · HVH1; MKP1; CL100; MKP-1; PTPN10. Summary. The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The …

WebDual specificity phosphatase 15 (Dusp15) represses myelin gene expression. Mag, Mbp, connexin 32 (Cx32), peripheral myelin protein 22 (Pmp22), and Srebp-1c mRNA levels were measured by quantitative RT-PCR in (a) RT4 Schwann cells, Dusp15 and Mag in (b) Primary Schwann cells treated with siRNA against Dusp15 and in (c and d) Dusp15-KO … included on an emailWebMar 7, 2006 · However, little is known on the functions of Ca 2+ /CaM-dependent protein kinases and phosphatases in Ca 2+ signaling in plants. From an Arabidopsis expression … included on an email thread brieflyWebDual specificity phosphatase 1 (DUSP1), a negative regulator of the mitogen‑activated protein kinase (MAPK) signaling pathway, has anti‑inflammatory properties. In the … inc5500WebJan 22, 2024 · Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism. Mitogen … included on or included inWebMore>> The Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI controls the biological activity of Dual Specificity Protein Phosphatase 1/6. Primarily used for Phosphorylation & Dephosphorylation apps. Less<< MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. ... inc594499WebMar 7, 2006 · However, little is known on the functions of Ca 2+ /CaM-dependent protein kinases and phosphatases in Ca 2+ signaling in plants. From an Arabidopsis expression library, we isolated cDNA encoding a dual-specificity protein phosphatase 1 (DsPTP1), which is capable of hydrolyzing both phosphoserine/threonine and phosphotyrosine … included on the balance sheet areWebDual-specificity phosphatase 6 (DUSP6): a review of its molecular characteristics and clinical relevance in cancer ... (ATF-2), activator protein 1 (AP-1),p53, and Elk, and also phosphorylates many cytoplasmic substrates, such as cytoskeletal proteins and mitochondrial proteins like Bcl-2 and Bcl-xl19,20. Subsequently, a plethora of cellular ... included on or in email