Webweight (TBW) as a percentage of ideal body weight (IBW).2, 3 But BMI does not scale pro-portionally to adipose tissue and lean muscle mass. Alternative size descriptors of body com-position include lean body weight (LBW), adjusted body weight (ABW; commonly with correction factors of 0.3 or 0.4, ABW 0.3 and WebDaptomycin plasma half-life, the fraction of the dose excreted unchanged in urine, and daptomycin absolute renal clearance (mL/h) were unchanged as a function of obesity. The absolute volume of distribution (Vz and Vss) and plasma clearance (CL) for daptomycin were higher in obese subjects as compared to nonobese matched controls.
Daptomycin Injection: Package Insert - Drugs.com
WebDose using a 40% adjusted body weight; Amphotericin B (liposomal) 3: Consider capping body weight to 100 kg; Atracurium 4: Dose using ideal body weight; The use of ideal … WebJan 1, 2024 · Following administration of a single 4 mg/kg dose of daptomycin by IV infusion over a 30-minute period, ... ¶ 99% Confidence Interval (adjusted for multiplicity) … fisher c404-32
Daptomycin dosing in obese patients: analysis of the …
WebNov 4, 2024 · Daptomycin is a lipopeptide antibiotic with activity against most clinically important gram-positive organisms, including resistant Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus faecium.Although dosed using total body weight (TBW), 1 alternative, … WebDose based on ideal body weight. Dosing in obesity (BMI > 30): use lean body weight (see online calculator). Drug is available in 400mg and 100mg tablets. This dosing aligns with … WebDaptomycin Dosing Based on Ideal Body Weight versus Actual Body ... (adjusted odds ratio of 2.10 for the IBW group, 95% confidence interval [CI] of 0.79 to 5.54, 80% CI of 1.11 to 3.16). Clinical canada\u0027s list of terrorist groups