site stats

Ctsh protein

WebImportant for the overall degradation of proteins in lysosomes. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase … WebThe cytoskeletal protein talin, an actin- and β-integrin tail-binding protein, plays an important role in cell migration by promoting integrin activation and focal adhesion formation. Here, we show that talin is a substrate for cathepsin H (CtsH), a lysosomal cysteine protease with a strong aminopeptidase activity. Purified active CtsH sequentially cleaved …

Pharos : Target Details - CTSH - National Institutes of Health

WebJan 30, 2024 · Another type 1 diabetes susceptibility gene, Cathepsin H (CTSH) [36, 37], is a lysosomal cysteine protease that is crucial for lysosomal protein degradation. Importantly, the CTSH susceptibility allele is associated with faster disease progression in newly diagnosed diabetes and reduced beta cell function in healthy humans . WebCTSH. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide … cu factory built insurance agency llc https://baileylicensing.com

NM_004390.5(CTSH):c.785A>G (p.Tyr262Cys) AND Inborn genetic …

WebFurthermore, the up-regulation of the CTSH protein in HepG2 cells after IR gave us a definitive answer to explain the phenomenon that the HepG2 cell was more resistant to radiation than the MHCC97H cell, in which the CTSH expression did not increase as significantly as in the HepG2 cell (Figure 2 e,i,j). From this perspective, we found a novel ... WebConsistent with extensive gene/protein characterization data. Consistent with extensive gene/protein characterization data. RNA consistency i High consistency between antibody staining and RNA expression data. High consistency between antibody staining and RNA expression data. ... CTSH-201. CTSH-207. CTSH-218. CTSH-232. CTSH-233. CTSH … WebCathepsin H (CTSH) is a type 1 diabetes (T1D) risk gene; large-scale genetic and epidemiological studies found that T1D genetic risk correlates with high CTSH … eastern bank in ma

Send us a Message - rgd.mcw.edu

Category:IJMS Free Full-Text Cathepsin H Knockdown Reverses …

Tags:Ctsh protein

Ctsh protein

NM_004390.5(CTSH):c.296C>T (p.Pro99Leu) AND Inborn genetic …

WebView mouse Ctsh Chr9:89936320-89958148 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression WebCTSH. HGNC Family. Minor histocompatibility antigens, Cathepsins (CTS) Name. cathepsin H. Description. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor.

Ctsh protein

Did you know?

WebCTSH; cathepsin H; Description From CBI Gene: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal … WebShowing 25 of 4,859 results for CTSH Search Time: 0 ms ... Ras Protein Specific Guanine Nucleotide Releasing Factor 1: Protein Coding: Q13972: 50: GC15M078959: 8.37: 3: ADAMTS7: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7: Protein Coding: Q9UKP4: 47: GC15M078759:

WebMar 21, 2024 · CTSH (Cathepsin H) is a Protein Coding gene. Diseases associated with CTSH include Narcolepsy 1 and Myopia. Among its related pathways are Innate Immune …

WebNM_004390.5(CTSH):c.296C>T (p.Pro99Leu) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Nov 29, 2024) Review status: 1 star out of maximum of 4 stars WebCTSH: Pro-cathepsin H; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family (335 aa) ... Pulmonary surfactant-associated protein …

WebCathepsin H. Cathepsin H is a protein that in humans is encoded by the CTSH gene. [5] [6] The protein encoded by this gene is a cysteine cathepsin, a lysosomal cysteine …

WebSep 1, 2024 · The CTSH protein expression exerted no . tissue speci city (Figure 6B). Besides the expression overview in normal tissue, the . abnormal expression of CTSH in cancer tissues was also . eastern bank in saugusWebThe protein expression overview (Figure 7B) suggested that higher expression appeared in prostate cancer, thyroid cancer and renal cancer. Among human cancers, both mRNA … eastern bank in westfordWebThe protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked … eastern bank interest ratesWebMar 11, 2024 · Cathepsin B (CTSB) is an exclusive multifunctional protein of cysteine protease family in that it has an additional pH sensitive occluding loop which allows it to … cu family medicine boulderWebProteome-wide association studies (PWASs) of AD found that variants rs12148472 and rs34593439 in the CTSH gene were associated with the CTSH protein abundance in human brain tissues [9, 33,34 ... eastern bank in saugus maWebCTSH INFORMATION. Proteini. Full gene name according to HGNC. Cathepsin H. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) Protein classi. Assigned HPA … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in amygdala … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in pancreas … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in midbrain tissue. … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in rectum tissue. … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in thyroid gland … GTEX-XYKS-2726-SM-4E3IC: 60-69 years, female: 93.2: GTEX-13OVL-0326-SM … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in fallopian tube … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in skin tissue. … Smooth Muscle - CTSH protein expression summary - The Human Protein Atlas Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in stomach tissue. … cu family health clinic sheridanWebProtein structure for human protein CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) We use cookies to enhance the usability of our website. If you continue, we'll assume that you … eastern bank in quincy massachusetts