Cromogranina wikipedia
WebAs graninas (cromogranina e secretogranina) formam uma família de proteínas ubiquitárias reguladoras de secreção proteica, que são encontradas nas vesículas … WebSep 21, 2016 · Chromogranin A (CgA) is an acidic glycoprotein with a molecular mass of 49 kd that is widely expressed by neuroendocrine cells and constitutes one of the most abundant components of secretory granules. 1 CgA is physiologically released by exocytosis and may be detected in the blood. In particular, when a tumor develops in an endocrine …
Cromogranina wikipedia
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WebLa cromogranina A o secrezione paratiroidea della proteina 1 è una proteina codificata dal gene CHGA, l'RNA del gene codifica per un membro della famiglia delle proteine … Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins. As such, it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in the pancreas. In humans, chromogranin A … See more Examples of cells producing chromogranin A (ChgA) are chromaffin cells of the adrenal medulla, paraganglia, enterochromaffin-like cells and beta cells of the pancreas. It is present in islet beta cell secretory granules. … See more Chromogranin A is elevated in pheochromocytomas. It has been identified as autoantigen in type 1 diabetes. A peptide fragment of ChgA located in the … See more • Hendy GN, Bevan S, Mattei MG, Mouland AJ (February 1995). "Chromogranin A". Clinical and Investigative Medicine. 18 (1): 47–65. PMID 7768066. • Iacangelo AL, Eiden LE (August 1995). "Chromogranin A: current status as a precursor for bioactive peptides and a granulogenic/sorting factor in the regulated secretory pathway" See more Chromogranin A is the precursor to several functional peptides including vasostatin-1, vasostatin-2, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells ( See more Variants exist for pancreastatin in various populations of the world. The variant Glycine297Serine has been shown to be more potent in inhibiting insulin-induced glucose uptake, resulting in higher risk of insulin resistance and diabetes among carriers of this … See more • chromogranin A antibody stains via Google Image [1] • Overview of all the structural information available in the PDB for UniProt: P10645 (Chromogranin-A) at the PDBe-KB. • Overview of all the structural information available in the PDB for UniProt: P26339 (Mouse … See more
WebClinical Information. Chromogranin A (CGA) is a 439-amino acid protein with a molecular weight of 48 to 60 kDa, depending on glycosylation and phosphorylation status. It is a member of the granin family of proteins and polypeptides. Granins are widespread in endocrine, neuroendocrine, peripheral, and central nervous tissues, where they are ... WebSerum Chromogranin A (CgA) CgA stabilises intracellular vesicles and regulates post-translational protein processing. It is elevated in between 60% and 100% of patients with …
WebSerum Chromogranin A (CgA) is the most established NET marker for diagnosis and monitoring progression or treatment response. CgA stabilises intracellular vesicles and regulates post-translational protein processing. WebChromogranin A antibody is an excellent marker for Carcinoid Tumors, Pheochromocytomas, Paragangliomas, and other Neuroendocrine Tumors. Coexpression of chromogranin A and neuron-specific enolase (NSE) is common in neuroendocrine neoplasms. It has been identified in a wide variety of endocrine tissues including the …
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WebChromogranin A (CGA) is a 439-amino acid protein with a molecular weight of 48 to 60 kDa, depending on glycosylation and phosphorylation status. It is a member of the granin family of proteins and polypeptides. Granins are widespread in endocrine, neuroendocrine, peripheral, and central nervous tissues, where they are found in secretory ... hoffman 17c swivel steam trapWebPurpose of review: The review summarizes the utility and limitations of chromogranin A (CgA) as a circulating biomarker for neuroendocrine tumors (NETs). Recent findings: Blood CgA measurement has numerous clinical limitations including poor assay reproducibility, low sensitivity (meta-analysis: 73%, 95% confidence interval: 0.71-0.76), and a paucity of … https now tvWebChromogranin A (CGA) is a 439-amino acid protein with a molecular weight of 48 to 60 kDa, depending on glycosylation and phosphorylation status. It is a member of the granin … https nw14 ultipro