WebSep 1, 2024 · Participants were randomized to receive PCb (paclitaxel 80 mg/m2 and carboplatin [area under the curve = 2] on days 1, 8, and 15 every 28 days for 6 cycles) or CEF-T (cyclophosphamide 500 mg/m2, epirubicin 100 mg/m2, and fluorouracil 500 mg/m2 every 3 weeks for 3 cycles followed by docetaxel 100 mg/m2 every 3 weeks for 3 cycles). WebMar 28, 2024 · Approximately two-thirds of patients with PDAC are diagnosed at a metastatic stage. 5 In this setting, the treatment relies on systemic chemotherapy, but …
Time-to-Treatment-Failure and Related Outcomes among 1000
WebFeb 25, 2016 · Patients who received weekly paclitaxel had a higher rate of grade 3 or 4 anemia than did those who received paclitaxel every 3 weeks (36% vs. 16%), as well as a higher rate of grade 2 to 4 ... WebMar 28, 2024 · Background: Chemotherapy options in patients with advanced pancreatic ductal adenocarcinoma (PDAC) after failure of standard chemotherapies are limited. Objectives: We aimed to report the efficacy and safety of the leucovorin and 5-fluorouracil (LV5FU2) and carboplatin combination in this setting. Design: We performed a … cleveland ohio editing jobs
Impact of obesity on chemotherapy dosing of carboplatin and …
WebDescriptions Carboplatin belongs to the group of medicines known as alkylating agents. It is used to treat cancer of the ovaries. It may also be used to treat other kinds of cancer, as determined by your doctor. Carboplatin interferes with the growth of cancer cells, which eventually are destroyed. WebOct 1, 1999 · The paclitaxel/carboplatin regimen was well tolerated by patients and caused fewer gastrointestinal, genitourinary, and metabolic effects, such as nausea, vomiting, weight loss, and kidney damage. The decrease in toxicity, however, was not associated with any decrease in efficacy. WebSep 25, 2024 · In conclusion, the addition of pembrolizumab to standard chemotherapy with carboplatin and either paclitaxel or nab-paclitaxel in patients with previously untreated metastatic, squamous NSCLC ... bmf audio